Human RGS20 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	RGS20
Locus ID	8601
Kit Components	GA105692G1, RGS20 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA105692G2, RGS20 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA105692G3, RGS20 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001286673, NM_001286674, NM_001286675, NM_003702, NM_170587, NR_104578, NR_104579
Synonyms	g(z)GAP; gz-GAP; RGSZ1; ZGAP1
Summary	The protein encoded by this gene belongs to the family of regulator of G protein signaling (RGS) proteins, which are regulatory and structural components of G protein-coupled receptor complexes. RGS proteins inhibit signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound forms. This protein selectively binds to G(z)-alpha and G(alpha)-i2 subunits, and regulates their signaling activities. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]

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