Human DcR3 (TNFRSF6B) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	TNFRSF6B
Locus ID	8771
Kit Components	GA105822G1, DcR3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA105822G2, DcR3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA105822G3, DcR3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_003823, NM_015647, NM_032945
Synonyms	DCR3; DJ583P15.1.1; M68; M68E; TR6
Summary	This gene belongs to the tumor necrosis factor receptor superfamily. The encoded protein is postulated to play a regulatory role in suppressing FasL- and LIGHT-mediated cell death. It acts as a decoy receptor that competes with death receptors for ligand binding. Over-expression of this gene has been noted in gastrointestinal tract tumors. Read-through transcription into this gene from the neighboring upstream gene, which encodes regulator of telomere elongation helicase 1 (RTEL1), generates a non-coding transcript. [provided by RefSeq, Feb 2011]

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