Human FLIP (CFLAR) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	CFLAR
Locus ID	8837
Kit Components	GA105879G1, FLIP gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA105879G2, FLIP gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA105879G3, FLIP gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001127183, NM_001127184, NM_001202515, NM_001202516, NM_001202517, NM_001202518, NM_001202519, NM_001308042, NM_001308043, NM_003879, NM_001351590, NM_001351591, NM_001351592, NM_001351593, NM_001351594, NR_147241, NR_147242, NR_147243, NR_147244, NR_147245, NR_147246, NR_147247, NR_147248, NR_147249, NR_147250, NR_147251, NR_147252, NR_147253, NR_147255
Synonyms	c-FLIP; c-FLIPL; c-FLIPR; c-FLIPS; CASH; CASP8AP1; Casper; CLARP; FLAME; FLAME-1; FLAME1; FLIP
Summary	The protein encoded by this gene is a regulator of apoptosis and is structurally similar to caspase-8. However, the encoded protein lacks caspase activity and appears to be itself cleaved into two peptides by caspase-8. Several transcript variants encoding different isoforms have been found for this gene, and partial evidence for several more variants exists. [provided by RefSeq, Feb 2011]

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