Human TSC22D1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	TSC22D1
Locus ID	8848
Kit Components	GA105888G1, TSC22D1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA105888G2, TSC22D1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA105888G3, TSC22D1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001243797, NM_001243798, NM_001243799, NM_006022, NM_183422
Synonyms	Ptg-2; TGFB1I4; TSC22
Summary	This gene encodes a member of the TSC22 domain family of leucine zipper transcription factors. The encoded protein is stimulated by transforming growth factor beta, and regulates the transcription of multiple genes including C-type natriuretic peptide. The encoded protein may play a critical role in tumor suppression through the induction of cancer cell apoptosis, and a single nucleotide polymorphism in the promoter of this gene has been associated with diabetic nephropathy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2011]

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