Human LDB1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	LDB1
Locus ID	8861
Kit Components	GA105898G1, LDB1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA105898G2, LDB1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA105898G3, LDB1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001113407, NM_003893, NM_001321612
Synonyms	CLIM2; NLI
Summary	Binds to the LIM domain of a wide variety of LIM domain-containing transcription factors. May regulate the transcriptional activity of LIM-containing proteins by determining specific partner interactions. Plays a role in the development of interneurons and motor neurons in cooperation with LHX3 and ISL1. Acts synergistically with LHX1/LIM1 in axis formation and activation of gene expression. Acts with LMO2 in the regulation of red blood cell development, maintaining erythroid precursors in an immature state (By similarity).[UniProtKB/Swiss-Prot Function]

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