Human ARHGEF7 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ARHGEF7
Locus ID	8874
Kit Components	GA105907G1, ARHGEF7 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA105907G2, ARHGEF7 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA105907G3, ARHGEF7 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001113511, NM_001113512, NM_001113513, NM_001320851, NM_001320852, NM_001320853, NM_001320854, NM_001330597, NM_001330598, NM_003899, NM_145735, NM_001354046, NM_001354047, NM_001354048, NM_001354049, NM_001354050, NM_001354051, NM_001354052, NM_001354053, NM_001354054, NM_001354055, NM_001354056, NM_001354057, NM_001354058, NM_001354059, NM_001354060, NM_001354061
Synonyms	BETA-PIX; COOL-1; COOL1; Nbla10314; P50; P50BP; P85; P85COOL1; P85SPR; PAK3; PIXB
Summary	This gene encodes a protein that belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP. It forms a complex with the small GTP binding protein Rac1 and recruits Rac1 to membrane ruffles and to focal adhesions. Multiple alternatively spliced transcript variants encoding different isoforms have been observed for this gene. [provided by RefSeq, Mar 2016]

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