Human TAF1C activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	TAF1C
Locus ID	9013
Kit Components	GA105988G1, TAF1C gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA105988G2, TAF1C gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA105988G3, TAF1C gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001243156, NM_001243157, NM_001243158, NM_001243159, NM_001243160, NM_005679, NM_139353
Synonyms	MGC:39976; SL1; TAFI95; TAFI110
Summary	Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding protein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I. This complex, known as SL1, binds to the core promoter of ribosomal RNA genes to position the polymerase properly and acts as a channel for regulatory signals. This gene encodes the largest SL1-specific TAF. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2011]

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