Human ASH2L activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ASH2L
Locus ID	9070
Kit Components	GA106033G1, ASH2L gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA106033G2, ASH2L gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA106033G3, ASH2L gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001105214, NM_001261832, NM_001282272, NM_004674, NR_049736
Synonyms	ASH2; ASH2L1; ASH2L2; Bre2
Summary	Component of the Set1/Ash2 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3, but not if the neighboring 'Lys-9' residue is already methylated. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. May function as a transcriptional regulator. May play a role in hematopoiesis.[UniProtKB/Swiss-Prot Function]

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