Human SLC33A1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	SLC33A1
Locus ID	9197
Kit Components	GA106131G1, SLC33A1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA106131G2, SLC33A1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA106131G3, SLC33A1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001190992, NM_004733, NM_001363883
Synonyms	ACATN; AT-1; AT1; CCHLND; SPG42
Summary	The protein encoded by this gene is required for the formation of O-acetylated (Ac) gangliosides. The encoded protein is predicted to contain 6 to 10 transmembrane domains, and a leucine zipper motif in transmembrane domain III. Defects in this gene have been reported to cause spastic paraplegia autosomal dominant type 42 (SPG42) in one Chinese family, but not in similar patients of European descent. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2010]

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