Human ITGB1BP1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ITGB1BP1
Locus ID	9270
Kit Components	GA106183G1, ITGB1BP1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA106183G2, ITGB1BP1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA106183G3, ITGB1BP1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001319066, NM_001319067, NM_001319068, NM_001319069, NM_001319070, NM_004763, NM_022334, NR_134951, NR_134952, NR_134953, NR_134954, NR_134955, NR_134956, NR_134957, NM_001369744, NM_001369746, NM_001369747, NM_001369749, NM_001369745, NM_001369748, NM_001369750
Synonyms	ICAP-1A; ICAP-1alpha; ICAP-1B; ICAP1; ICAP1A; ICAP1B
Summary	The cytoplasmic domains of integrins are essential for cell adhesion. The protein encoded by this gene binds to the beta1 integrin cytoplasmic domain. The interaction between this protein and beta1 integrin is highly specific. Two isoforms of this protein are derived from alternatively spliced transcripts. The shorter form of this protein does not interact with the beta1 integrin cytoplasmic domain. The longer form is a phosphoprotein and the extent of its phosphorylation is regulated by the cell-matrix interaction, suggesting an important role of this protein during integrin-dependent cell adhesion. Several transcript variants, some protein-coding and some non-protein coding, have been found for this gene. [provided by RefSeq, Jan 2016]

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