Human EI24 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	EI24
Locus ID	9538
Kit Components	GA106383G1, EI24 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA106383G2, EI24 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA106383G3, EI24 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001007277, NM_001290135, NM_004879, NR_110769, NR_110770, NM_001330419
Synonyms	EPG4; PIG8; TP53I8
Summary	This gene encodes a putative tumor suppressor and has higher expression in p53-expressing cells than in control cells and is an immediate-early induction target of p53-mediated apoptosis. The encoded protein may suppress cell growth by inducing apoptotic cell death through the caspase 9 and mitochondrial pathways. This gene is located on human chromosome 11q24, a region frequently altered in cancers. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene have been defined on chromosomes 1, 3, 7, and 8. [provided by RefSeq, Feb 2014]

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