Human Synphilin 1 (SNCAIP) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	SNCAIP
Locus ID	9627
Kit Components	GA106447G1, Synphilin 1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA106447G2, Synphilin 1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA106447G3, Synphilin 1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001242935, NM_001308100, NM_001308105, NM_001308106, NM_001308107, NM_001308108, NM_001308109, NM_005460, NR_131761, NR_131762, N21998
Synonyms	Sph1; SYPH1
Summary	This gene encodes a protein containing several protein-protein interaction domains, including ankyrin-like repeats, a coiled-coil domain, and an ATP/GTP-binding motif. The encoded protein interacts with alpha-synuclein in neuronal tissue and may play a role in the formation of cytoplasmic inclusions and neurodegeneration. A mutation in this gene has been associated with Parkinson's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]

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