Human IKBKE activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	IKBKE
Locus ID	9641
Kit Components	GA106459G1, IKBKE gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA106459G2, IKBKE gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA106459G3, IKBKE gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001193321, NM_001193322, NM_014002
Synonyms	IKK-E; IKK-i; IKKE; IKKI
Summary	IKBKE is a noncanonical I-kappa-B (see MIM 164008) kinase (IKK) that is essential for regulating antiviral signaling pathways. IKBKE has also been identified as a breast cancer (MIM 114480) oncogene and is amplified and overexpressed in over 30% of breast carcinomas and breast cancer cell lines (Hutti et al., 2009 [PubMed 19481526]).[supplied by OMIM, Oct 2009]

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