Human RIM2 (RIMS2) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	RIMS2
Locus ID	9699
Kit Components	GA106510G1, RIM2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA106510G2, RIM2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA106510G3, RIM2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001100117, NM_001282881, NM_001282882, NM_014677, NM_001348484, NM_001348485, NM_001348486, NM_001348487, NM_001348488, NM_001348489, NM_001348490, NM_001348491, NM_001348492, NM_001348493, NM_001348494, NM_001348495, NM_001348496, NM_001348497, NM_001348498, NM_001348499, NM_001348500, NM_001348501, NM_001348502, NM_001348503, NM_001348504, NM_001348505, NM_001348506, NM_001348507, NM_001348508, NM_001348509, NR_145710, NR_145711
Synonyms	OBOE; RAB3IP3; RIM2
Summary	The protein encoded by this gene is a presynaptic protein that interacts with RAB3, a protein important for normal neurotransmitter release. The encoded protein can also bind several other synaptic proteins, including UNC-13 homolog B, ELKS/Rab6-interacting/CAST family member 1, and synaptotagmin 1. This protein is involved in synaptic membrane exocytosis. Polymorphisms in this gene have been associated with degenerative lumbar scoliosis. [provided by RefSeq, Feb 2017]

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