Human RNF40 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	RNF40
Locus ID	9810
Kit Components	GA106607G1, RNF40 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA106607G2, RNF40 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA106607G3, RNF40 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001207033, NM_001207034, NM_001286572, NM_014771, NM_194352
Synonyms	BRE1B; RBP95; STARING
Summary	The protein encoded by this gene contains a RING finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein was reported to interact with the tumor suppressor protein RB1. Studies of the rat counterpart suggested that this protein may function as an E3 ubiquitin-protein ligase, and facilitate the ubiquitination and degradation of syntaxin 1, which is an essential component of the neurotransmitter release machinery. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011]

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