Human PDCD6 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	PDCD6
Locus ID	10016
Kit Components	GA106784G1, PDCD6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA106784G2, PDCD6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA106784G3, PDCD6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001267556, NM_001267557, NM_001267558, NM_001267559, NM_013232, NR_073609
Synonyms	ALG-2; ALG2; PEF1B
Summary	This gene encodes a calcium-binding protein belonging to the penta-EF-hand protein family. Calcium binding is important for homodimerization and for conformational changes required for binding to other protein partners. This gene product participates in T cell receptor-, Fas-, and glucocorticoid-induced programmed cell death. In mice deficient for this gene product, however, apoptosis was not blocked suggesting this gene product is functionally redundant. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is also located on the short arm of chromosome 5. [provided by RefSeq, May 2012]

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