Human MBNL2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	MBNL2
Locus ID	10150
Kit Components	GA106891G1, MBNL2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA106891G2, MBNL2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA106891G3, MBNL2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001306070, NM_005757, NM_144778, NM_207304
Synonyms	MBLL; MBLL39; PRO2032
Summary	This gene is a member of the muscleblind protein family which was initially described in Drosophila melanogaster. This gene encodes a C3H-type zinc finger protein that modulates alternative splicing of pre-mRNAs. Muscleblind proteins bind specifically to expanded dsCUG RNA but not to normal size CUG repeats and may thereby play a role in the pathophysiology of myotonic dystrophy. Several alternatively spliced transcript variants have been described but the full-length natures of only some have been determined. [provided by RefSeq, Mar 2012]

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