Human ALG3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ALG3
Locus ID	10195
Kit Components	GA106925G1, ALG3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA106925G2, ALG3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA106925G3, ALG3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001006940, NM_001006941, NM_001006942, NM_005787, NR_024533, NR_024534
Synonyms	CDGS4; D16Ertd36e; Not56; NOT56L
Summary	This gene encodes a member of the ALG3 family. The encoded protein catalyses the addition of the first dol-P-Man derived mannose in an alpha 1,3 linkage to Man5GlcNAc2-PP-Dol. Defects in this gene have been associated with congenital disorder of glycosylation type Id (CDG-Id) characterized by abnormal N-glycosylation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2008]

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