Human OLIG2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	OLIG2
Locus ID	10215
Kit Components	GA106945G1, OLIG2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA106945G2, OLIG2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA106945G3, OLIG2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_005806
Synonyms	BHLHB1; bHLHe19; OLIGO2; PRKCBP2; RACK17
Summary	This gene encodes a basic helix-loop-helix transcription factor which is expressed in oligodendroglial tumors of the brain. The protein is an essential regulator of ventral neuroectodermal progenitor cell fate. The gene is involved in a chromosomal translocation t(14;21)(q11.2;q22) associated with T-cell acute lymphoblastic leukemia. Its chromosomal location is within a region of chromosome 21 which has been suggested to play a role in learning deficits associated with Down syndrome. [provided by RefSeq, Jul 2008]

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