Human KLRG1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	KLRG1
Locus ID	10219
Kit Components	GA106949G1, KLRG1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA106949G2, KLRG1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA106949G3, KLRG1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001329099, NM_001329101, NM_001329102, NM_001329103, NM_005810, NR_137426, NR_137427, NR_137428
Synonyms	2F1; CLEC15A; MAFA; MAFA-2F1; MAFA-L; MAFA-LIKE
Summary	Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor (KLR) family, which is a group of transmembrane proteins preferentially expressed in NK cells. Studies in mice suggested that the expression of this gene may be regulated by MHC class I molecules. [provided by RefSeq, Jun 2016]

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