Human DSCR1L1 (RCAN2) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	RCAN2
Locus ID	10231
Kit Components	GA106959G1, DSCR1L1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA106959G2, DSCR1L1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA106959G3, DSCR1L1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001251973, NM_001251974, NM_005822
Synonyms	CSP2; DSCR1L1; MCIP2; RCN2; ZAKI-4; ZAKI4
Summary	This gene encodes a member of the regulator of calcineurin (RCAN) protein family. These proteins play a role in many physiological processes by binding to the catalytic domain of calcineurin A, inhibiting calcineurin-mediated nuclear translocation of the transcription factor NFATC1. Expression of this gene in skin fibroblasts is upregulated by thyroid hormone, and the encoded protein may also play a role in endothelial cell function and angiogenesis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011]

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