Human RASGRP2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	RASGRP2
Locus ID	10235
Kit Components	GA106963G1, RASGRP2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA106963G2, RASGRP2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA106963G3, RASGRP2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001098670, NM_001098671, NM_001318398, NM_005825, NM_153819
Synonyms	CALDAG-GEFI; CDC25L
Summary	The protein encoded by this gene is a brain-enriched nucleotide exchanged factor that contains an N-terminal GEF domain, 2 tandem repeats of EF-hand calcium-binding motifs, and a C-terminal diacylglycerol/phorbol ester-binding domain. This protein can activate small GTPases, including RAS and RAP1/RAS3. The nucleotide exchange activity of this protein can be stimulated by calcium and diacylglycerol. Four alternatively spliced transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jan 2016]

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