Human HE4 (WFDC2) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	WFDC2
Locus ID	10406
Kit Components	GA107093G1, HE4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA107093G2, HE4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA107093G3, HE4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_006103, NM_080733, NM_080734, NM_080735, NM_080736
Synonyms	dJ461P17.6; EDDM4; HE4; WAP5
Summary	This gene encodes a protein that is a member of the WFDC domain family. The WFDC domain, or WAP Signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. This gene is expressed in pulmonary epithelial cells, and was also found to be expressed in some ovarian cancers. The encoded protein is a small secretory protein, which may be involved in sperm maturation. [provided by RefSeq, Jul 2008]

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