Human RBM14 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	RBM14
Locus ID	10432
Kit Components	GA107113G1, RBM14 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA107113G2, RBM14 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA107113G3, RBM14 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001198836, NM_001198837, NM_006328
Synonyms	COAA; PSP2; SIP; SYTIP1; TMEM137
Summary	This gene encodes a ribonucleoprotein that functions as a general nuclear coactivator, and an RNA splicing modulator. This protein contains two RNA recognition motifs (RRM) at the N-terminus, and multiple hexapeptide repeat domain at the C-terminus that interacts with thyroid hormone receptor-binding protein (TRBP), and is required for transcription activation. Alternatively spliced transcript variants encoding different isoforms (with opposing effects on transcription) have been described for this gene. [provided by RefSeq, Oct 2011]

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