Human CIB2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	CIB2
Locus ID	10518
Kit Components	GA107184G1, CIB2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA107184G2, CIB2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA107184G3, CIB2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001271888, NM_001271889, NM_001301224, NM_006383, NR_125435
Synonyms	DFNB48; KIP2; USH1J
Summary	The protein encoded by this gene is similar to that of KIP/CIB, calcineurin B, and calmodulin. The encoded protein is a calcium-binding regulatory protein that interacts with DNA-dependent protein kinase catalytic subunits (DNA-PKcs), and it is involved in photoreceptor cell maintenance. Mutations in this gene cause deafness, autosomal recessive, 48 (DFNB48), and also Usher syndrome 1J (USH1J). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]

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