Human Ubiquitin D (UBD) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	UBD
Locus ID	10537
Kit Components	GA107201G1, Ubiquitin D gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA107201G2, Ubiquitin D gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA107201G3, Ubiquitin D gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_006398
Synonyms	FAT10; GABBR1; UBD-3
Summary	This gene encodes a protein which contains two ubiquitin-like domains and appears to have similar function to ubiquitin. Through covalent attachment, the encoded protein targets other proteins for 26S proteasome degradation. This protein has been implicated to function in many cellular processes, including caspase-dependent apoptosis, formation of aggresomes, mitotic regulation, and dendritic cell maturation. Upregulation of this gene may promote inflammation in chronic kidney disease and has been observed in many cancer types. [provided by RefSeq, Aug 2017]

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