Human MTHFS activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	MTHFS
Locus ID	10588
Kit Components	GA107245G1, MTHFS gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA107245G2, MTHFS gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA107245G3, MTHFS gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001199758, NM_006441, NR_037654
Synonyms	HsT19268
Summary	The protein encoded by this gene is an enzyme that catalyzes the conversion of 5-formyltetrahydrofolate to 5,10-methenyltetrahydrofolate, a precursor of reduced folates involved in 1-carbon metabolism. An increased activity of the encoded protein can result in an increased folate turnover rate and folate depletion. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jun 2011]

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