Human IRE1 (ERN2) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ERN2
Locus ID	10595
Kit Components	GA107251G1, IRE1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA107251G2, IRE1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA107251G3, IRE1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001308220, NM_033266
Synonyms	hIRE2p; IRE1-BETA; IRE1b; IRE2p
Summary	Induces translational repression through 28S ribosomal RNA cleavage in response to ER stress. Pro-apoptotic. Appears to play no role in the unfolded-protein response, unlike closely related proteins.[UniProtKB/Swiss-Prot Function]

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