Human SPINT2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	SPINT2
Locus ID	10653
Kit Components	GA107301G1, SPINT2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA107301G2, SPINT2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA107301G3, SPINT2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001166103, NM_021102
Synonyms	DIAR3; HAI-2; HAI2; Kop; PB
Summary	This gene encodes a transmembrane protein with two extracellular Kunitz domains that inhibits a variety of serine proteases. The protein inhibits HGF activator which prevents the formation of active hepatocyte growth factor. This gene is a putative tumor suppressor, and mutations in this gene result in congenital sodium diarrhea. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]

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