Human DMRT2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	DMRT2
Locus ID	10655
Kit Components	GA107303G1, DMRT2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA107303G2, DMRT2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA107303G3, DMRT2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001130865, NM_006557, NM_181872, NM_001370531, NM_001370532, NM_001370533, NR_163472
Synonyms	doublesex and mab-3 related transcription factor 2; OTTHUMP00000020964; OTTHUMP00000020965; OTTHUMP00000020966; OTTHUMP00000020967; terra-like protein
Summary	The protein encoded by this gene belongs to the DMRT gene family, sharing a DM DNA-binding domain with Drosophila 'doublesex' (dsx) and C. elegans mab3, genes involved in sex determination in these organisms. Also, this gene is located in a region of the human genome (chromosome 9p24.3) associated with gonadal dysgenesis and XY sex reversal. Hence this gene is one of the candidates for sex-determining gene(s) on chr 9. [provided by RefSeq, Apr 2010]

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