Human MEKK2 (MAP3K2) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	MAP3K2
Locus ID	10746
Kit Components	GA107364G1, MEKK2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA107364G2, MEKK2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA107364G3, MEKK2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_006609
Synonyms	MEKK2; MEKK2B
Summary	The protein encoded by this gene is a member of serine/threonine protein kinase family. This kinase preferentially activates other kinases involved in the MAP kinase signaling pathway. This kinase has been shown to directly phosphorylate and activate Ikappa B kinases, and thus plays a role in NF-kappa B signaling pathway. This kinase has also been found to bind and activate protein kinase C-related kinase 2, which suggests its involvement in a regulated signaling process. [provided by RefSeq, Jul 2008]

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