Human KDM5B activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	KDM5B
Locus ID	10765
Kit Components	GA107375G1, KDM5B gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA107375G2, KDM5B gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA107375G3, KDM5B gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_006618, NM_001314042, NM_001347591
Synonyms	CT31; JARID1B; PLU-1; PLU1; PPP1R98; PUT1; RBBP2H1A
Summary	This gene encodes a lysine-specific histone demethylase that belongs to the jumonji/ARID domain-containing family of histone demethylases. The encoded protein is capable of demethylating tri-, di- and monomethylated lysine 4 of histone H3. This protein plays a role in the transcriptional repression or certain tumor suppressor genes and is upregulated in certain cancer cells. This protein may also play a role in genome stability and DNA repair. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Nov 2016]

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