Human TXNL4A activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	TXNL4A
Locus ID	10907
Kit Components	GA107477G1, TXNL4A gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA107477G2, TXNL4A gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA107477G3, TXNL4A gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001303471, NM_001305557, NM_001305563, NM_001305564, NM_006701, NR_131175, NR_131176, NR_131177
Synonyms	BMKS; DIB1; DIM1; SNRNP15; TXNL4; U5-15kD
Summary	The protein encoded by this gene is a member of the U5 small ribonucleoprotein particle (snRNP), and is involved in pre-mRNA splicing. This protein contains a thioredoxin-like fold and it is expected to interact with multiple proteins. Protein-protein interactions have been observed with the polyglutamine tract-binding protein 1 (PQBP1). Mutations in both the coding region and promoter region of this gene have been associated with Burn-McKeown syndrome, which is a rare disorder characterized by craniofacial dysmorphisms, cardiac defects, hearing loss, and bilateral choanal atresia. A pseudogene of this gene is found on chromosome 2. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2015]

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