Human Urotensin II (UTS2) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	UTS2
Locus ID	10911
Kit Components	GA107480G1, Urotensin II gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA107480G2, Urotensin II gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA107480G3, Urotensin II gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_006786, NM_021995
Synonyms	PRO1068; U-II; UCN2; UII
Summary	This gene encodes a mature peptide that is an active cyclic heptapeptide absolutely conserved from lamprey to human. The active peptide acts as a vasoconstrictor and is expressed only in brain tissue. Despite the gene family name similarity, this gene is not homologous to urocortin, a member of the sauvagine/corticotropin-releasing factor/urotensin I family. Most of the proprotein is cleaved to make the mature peptide. Transcript variants encoding different preproprotein isoforms have been described for this gene. [provided by RefSeq, Jul 2008]

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