Human SF3A3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	SF3A3
Locus ID	10946
Kit Components	GA107509G1, SF3A3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA107509G2, SF3A3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA107509G3, SF3A3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001320830, NM_006802, N67022, N91991
Synonyms	PRP9; PRPF9; SAP61; SF3a60
Summary	This gene encodes subunit 3 of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer includes subunits 1, 2 and 3 and is necessary for the in vitro conversion of 15S U2 snRNP into an active 17S particle that performs pre-mRNA splicing. Subunit 3 interacts with subunit 1 through its amino-terminus while the zinc finger domain of subunit 3 plays a role in its binding to the 15S U2 snRNP. This gene has a pseudogene on chromosome 20. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]

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