Human Kallikrein 11 (KLK11) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	KLK11
Locus ID	11012
Kit Components	GA107562G1, Kallikrein 11 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA107562G2, Kallikrein 11 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA107562G3, Kallikrein 11 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001136032, NM_001167605, NM_006853, NM_144947
Synonyms	PRSS20; TLSP
Summary	Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Alternate splicing and the use of alternate promoters results in multiple transcript variants encoding distinct isoforms which are differentially expressed. [provided by RefSeq, Dec 2016]

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