Human ADRM1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ADRM1
Locus ID	11047
Kit Components	GA107591G1, ADRM1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA107591G2, ADRM1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA107591G3, ADRM1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001281437, NM_001281438, NM_007002, NM_175573
Synonyms	ARM-1; ARM1; GP110
Summary	This gene encodes a member of the adhesion regulating molecule 1 protein family. The encoded protein is a component of the proteasome where it acts as a ubiquitin receptor and recruits the deubiquitinating enzyme, ubiquitin carboxyl-terminal hydrolase L5. Increased levels of the encoded protein are associated with increased cell adhesion, which is likely an indirect effect of this intracellular protein. Dysregulation of this gene has been implicated in carcinogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

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