Human ABHD2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ABHD2
Locus ID	11057
Kit Components	GA107597G1, ABHD2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA107597G2, ABHD2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA107597G3, ABHD2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_007011, NM_152924
Synonyms	HS1-2; LABH2; PHPS1-2
Summary	This gene encodes a protein containing an alpha/beta hydrolase fold, which is a catalytic domain found in a wide range of enzymes. The encoded protein is an acylglycerol lipase that catalyzes the hydrolysis of endocannabinoid arachidonoylglycerol from the cell membrane. This leads to activation of the sperm calcium channel CatSper, which results in sperm activation. Alternative splicing of this gene results in two transcript variants encoding the same protein. [provided by RefSeq, Jan 2017]

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