Human SOX30 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	SOX30
Locus ID	11063
Kit Components	GA107602G1, SOX30 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA107602G2, SOX30 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA107602G3, SOX30 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001308165, NM_007017, NM_178424
Synonyms	Sox30 protein type II; SRY (sex determining region Y)-box 30
Summary	This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein acts as a transcriptional regulator when present in a complex with other proteins. It can activate p53 transcription to promote tumor cell apoptosis in lung cancer. The protein may be involved in the differentiation of developing male germ cells. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 5. [provided by RefSeq, Apr 2015]

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