Human Epac2 (RAPGEF4) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	RAPGEF4
Locus ID	11069
Kit Components	GA107608G1, Epac2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA107608G2, Epac2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA107608G3, Epac2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001100397, NM_001282899, NM_001282900, NM_001282901, NM_007023
Synonyms	CAMP-GEFII; CGEF2; EPAC; EPAC 2; EPAC2; Nbla00496
Summary	Guanine nucleotide exchange factor (GEF) for RAP1A, RAP1B and RAP2A small GTPases that is activated by binding cAMP. Seems not to activate RAB3A. Involved in cAMP-dependent, PKA-independent exocytosis through interaction with RIMS2 (By similarity).[UniProtKB/Swiss-Prot Function]

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