Human TRIOBP activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	TRIOBP
Locus ID	11078
Kit Components	GA107616G1, TRIOBP gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA107616G2, TRIOBP gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA107616G3, TRIOBP gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001039141, NM_007032, NM_138632
Synonyms	DFNB28; dJ37E16.4; HRIHFB2122; TAP68; TARA
Summary	This gene encodes a protein with an N-terminal pleckstrin homology domain and a C-terminal coiled-coil region. The protein interacts with trio, which is involved with neural tissue development and controlling actin cytoskeleton organization, cell motility and cell growth. The protein also associates with F-actin and stabilizes F-actin structures. Mutations in this gene have been associated with a form of autosomal recessive nonsyndromic deafness. Multiple alternatively spliced transcript variants that would encode different isoforms have been found for this gene, however some transcripts may be subject to nonsense-mediated decay (NMD). [provided by RefSeq, Nov 2008]

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