Human CEP250 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	CEP250
Locus ID	11190
Kit Components	GA107711G1, CEP250 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA107711G2, CEP250 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA107711G3, CEP250 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001035518, NM_001318219, NM_007186
Synonyms	C-NAP1; centrosomal Nek2-associated protein 1; centrosomal protein, 250-KD; centrosomal protein 2; centrosomal protein 250kDa; centrosome associated protein; CEP2; CNAP1; MGC88542; OTTHUMP00000030757
Summary	This gene encodes a core centrosomal protein required for centriole-centriole cohesion during interphase of the cell cycle. The encoded protein dissociates from the centrosomes when parental centrioles separate at the beginning of mitosis. The protein associates with and is phosphorylated by NIMA-related kinase 2, which is also associated with the centrosome. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015]

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