Human PLPBP activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	PLPBP
Locus ID	11212
Kit Components	GA107722G1, PLPBP gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA107722G2, PLPBP gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA107722G3, PLPBP gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_007198, NM_001349346, NM_001349347, NM_001349348, NM_001349349
Synonyms	FLJ11861
Summary	This gene encodes a pyridoxal 5'-phosphate binding protein involved in the homeostatic regulation of intracellular pyridoxal 5'-phosphate. This gene has a tumor suppressive effect on hepatocellular carcinoma and other solid tumors of epithelial origin. Naturally occurring mutations in this gene are associated with a pyridoxine-dependent epilepsy. [provided by RefSeq, Mar 2017]

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