Human IRAKM (IRAK3) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	IRAK3
Locus ID	11213
Kit Components	GA107723G1, IRAKM gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA107723G2, IRAKM gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA107723G3, IRAKM gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001142523, NM_007199
Synonyms	ASRT5; IRAKM
Summary	This gene encodes a member of the interleukin-1 receptor-associated kinase protein family. Members of this family are essential components of the Toll/IL-R immune signal transduction pathways. This protein is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling. Mutations in this gene are associated with a susceptibility to asthma. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2010]

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