Human AKAP10 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	AKAP10
Locus ID	11216
Kit Components	GA107726G1, AKAP10 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA107726G2, AKAP10 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA107726G3, AKAP10 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_007202, NM_001330152
Synonyms	AKAP-10; D-AKAP-2; D-AKAP2; PRKA10
Summary	This gene encodes a member of the A-kinase anchor protein family. A-kinase anchor proteins bind to the regulatory subunits of protein kinase A (PKA) and confine the holoenzyme to discrete locations within the cell. The encoded protein is localized to mitochondria and interacts with both the type I and type II regulatory subunits of PKA. Polymorphisms in this gene may be associated with increased risk of arrhythmias and sudden cardiac death. [provided by RefSeq, May 2012]

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