Human RASSF8 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	RASSF8
Locus ID	11228
Kit Components	GA107735G1, RASSF8 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA107735G2, RASSF8 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA107735G3, RASSF8 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001164746, NM_001164747, NM_001164748, NM_007211
Synonyms	C12orf2; HOJ1
Summary	This gene encodes a member of the Ras-assocation domain family (RASSF) of tumor suppressor proteins. This gene is essential for maintaining adherens junction function in epithelial cells and has a role in epithelial cell migration. It is a lung tumor suppressor gene candidate. A chromosomal translocation t(12;22)(p11.2;q13.3) leading to the fusion of this gene and the FBLN1 gene is found in a complex type of synpolydactyly. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011]

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