Human PARK7 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	PARK7
Locus ID	11315
Kit Components	GA107785G1, PARK7 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA107785G2, PARK7 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA107785G3, PARK7 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001123377, NM_007262
Synonyms	DJ-1; DJ1; HEL-S-67p
Summary	The product of this gene belongs to the peptidase C56 family of proteins. It acts as a positive regulator of androgen receptor-dependent transcription. It may also function as a redox-sensitive chaperone, as a sensor for oxidative stress, and it apparently protects neurons against oxidative stress and cell death. Defects in this gene are the cause of autosomal recessive early-onset Parkinson disease 7. Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008]

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