Human TRAK1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	TRAK1
Locus ID	22906
Kit Components	GA107901G1, TRAK1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA107901G2, TRAK1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA107901G3, TRAK1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001042646, NM_001265608, NM_001265609, NM_001265610, NM_014965, NM_001349245, NM_001349246, NM_001349247, NM_001349248, NM_001349249, NR_146089
Synonyms	MILT1; OIP106
Summary	Involved in the regulation of endosome-to-lysosome trafficking, including endocytic trafficking of EGF-EGFR complexes and GABA-A receptors (PubMed:18675823). Involved in mitochondrial motility. When O-glycosylated, abolishes mitochondrial motility. Crucial for recruiting OGT to the mitochondrial surface of neuronal processes (PubMed:24995978). TRAK1 and RHOT form an essential protein complex that links KIF5 to mitochondria for light chain-independent, anterograde transport of mitochondria (By similarity).[UniProtKB/Swiss-Prot Function]

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