Human PDZK3 (PDZD2) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	PDZD2
Locus ID	23037
Kit Components	GA107989G1, PDZK3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA107989G2, PDZK3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA107989G3, PDZK3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_015022, NM_178140
Synonyms	AIPC; KIAA0300; PAPIN; PDZD2; PIN1
Summary	The protein encoded by this gene contains six PDZ domains and shares sequence similarity with pro-interleukin-16 (pro-IL-16). Like pro-IL-16, the encoded protein localizes to the endoplasmic reticulum and is thought to be cleaved by a caspase to produce a secreted peptide containing two PDZ domains. In addition, this gene is upregulated in primary prostate tumors and may be involved in the early stages of prostate tumorigenesis. [provided by RefSeq, Dec 2015]

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