Human IQSEC2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	IQSEC2
Locus ID	23096
Kit Components	GA108035G1, IQSEC2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA108035G2, IQSEC2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA108035G3, IQSEC2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001111125, NM_001243197, NM_015075, NR_024449
Synonyms	BRAG1; MRX1
Summary	This gene encodes a guanine nucleotide exchange factor for the ARF family of small GTP-binding proteins. The encoded protein is a component of the postsynaptic density at excitatory synapses, and may play a critical role in cytoskeletal and synaptic organization through the activation of selected ARF substrates including ARF1 and ARF6. Mutations in this gene have been implicated in nonsyndromic X-linked cognitive disability. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2011]

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